[Objective] This paper illustrated the influencing factors of water resource security and its evolution trend aimed to put forward some suggestions about the water resource security in Karst area.[Methods] Based on the data of Guizhou Province in the past ten years

this paper established a BP network model and applied the mean impact value(MIV) algorithm method to analyze the influencing factors of the water resource security in Karst area.[Results] The groundwater supply ratio

the industrial water use proportion

water use efficiency

per capital grain yield and water yield modulus were the obstacles to the development of water resources system. The influencing degree of water yield modulus was decreasing year by year

while the other four factors showed increasing trends. Comprehensive utilization rate of industrial solid waste

the attainment rate of the industrial waste water

the ratio of moderate rocky desertification area

water requirement per-unit GDP and exploitation degree of groundwater were the driving factors. In chronological order

the influence of water requirement of per-unit GDP and exploitation degree of groundwater were stable

while the ratio of moderate rocky desertification area was more and more pronounced. The impact of the attainment rate of the industrial waste water decreased year by year

while comprehensive utilization rate of industrial solid waste fluctuated greatly.[Conclusion] The MIV-BP model is feasible in studying influencing factors of water resource security in karst area.